Cancer Genes & Pathways
Search a curated gene profile, or move from a mutation to the signalling pathway and evidence that explain its cancer relevance.
Start with the strongest guides
Follow a gene from mutation to pathway to therapy resistance
These linked guides separate gene-level function, pathway-level mechanism, and research interpretation so each page answers a distinct question.
Cornerstone pathway
EGFR signalling in cancer
Receptor activation, RAS–MAPK and PI3K branches, NSCLC mutations, and resistance.
Focused article
EGFR mutations and targeted therapy
A treatment-focused explanation of sensitising mutations, inhibitors, and escape mechanisms.
Gene profile
TP53 function and cancer
A complete, source-linked profile of p53 regulation, checkpoints, mutation effects, and disease context.
Clinical Trials News
A daily, plain-language digest of new oncology and life-sciences clinical trials, with a weekly deep-dive roundup — every update linked to its trial registry or primary source.
Open the newsletter